Pharma & Materials Science

Materials Discovery Platform

AI-powered discovery platform for pharmaceutical and metallurgical materials with ML predictions, ADMET screening, and comprehensive database management

Dual-Domain Discovery System

Advanced platform combining drug discovery and materials science screening capabilities. Assess bioavailability, toxicity, and drug-likeness while simultaneously predicting mechanical, thermal, and electronic properties of metallurgical materials.

Features include Lipinski's Rule of Five validation, PAINS screening, corrosion resistance analysis, and high-temperature stability assessments with interactive web dashboard and RESTful API integration.

System Capabilities

Chemistry RDKit & PyMatGen
ML Framework Scikit-learn
API Flask RESTful
Database SQLite/PostgreSQL

Core Capabilities

ADMET Screening

Comprehensive assessment of bioavailability, toxicity, solubility, and permeability with Lipinski's Rule of Five validation.

Property Prediction

ML-powered prediction of mechanical, thermal, and electronic properties for alloys and compounds.

Batch Processing

Screen multiple compounds and materials simultaneously with tracking and export to CSV/JSON formats.

Rule-Based Filters

Lipinski's Rule of Five, Veber rules, and PAINS screening for drug-like property validation.

Interactive Dashboard

Web-based visualization with Plotly charts for molecular descriptors and material properties.

Optimization Suggestions

AI-generated recommendations to improve drug-like properties and material performance characteristics.

Technical Specifications

Chemistry
RDKit
Materials Science
PyMatGen
ML Framework
Scikit-learn
Web Framework
Flask + SQLAlchemy
Visualization
Plotly
Database
SQLite/PostgreSQL
Analysis
NumPy + Pandas
Deployment
Gunicorn/NGINX

Getting Started

Quick setup guide for Materials Discovery Platform

1

Run Setup Script

chmod +x setup.sh run.sh
./setup.sh
2

Configure Environment

# Edit .env file
DATABASE_URL=sqlite:///discovery.db
FLASK_ENV=development
3

Start Application

./run.sh
# Access http://localhost:5000
4

Test with Examples

Drug: CC(=O)OC1=CC=CC=C1C(=O)O (Aspirin)
Material: Fe18Cr8Ni (Stainless Steel)

Ready to Accelerate Discovery?

Combine pharmaceutical and materials science screening in one platform